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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MATK All Species: 11.52
Human Site: Y420 Identified Species: 23.03
UniProt: P42679 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42679 NP_002369.2 507 56469 Y420 L L W E V F S Y G R A P Y P K
Chimpanzee Pan troglodytes XP_512276 328 36052 V254 K H G S L K E V S E A V E K G
Rhesus Macaque Macaca mulatta XP_001101430 450 50702 L376 V W S F G I L L W E I Y S F G
Dog Lupus familis XP_854815 843 91685 Y659 L L W E V F S Y G R A P Y P K
Cat Felis silvestris
Mouse Mus musculus P41242 505 56038 Y418 L L W E V F S Y G R A P Y P K
Rat Rattus norvegicus P41243 467 51878 V393 P K M S L K E V S E A V E K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P41239 450 50733 L376 V W S F G I L L W E I Y S F G
Frog Xenopus laevis P13116 532 59718 K457 L L T E L T T K G R V P Y P G
Zebra Danio Brachydanio rerio XP_695792 445 50295 V371 S D V W S Y G V L L W E I F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731611 1052 113728 F976 N K S D M W S F G I L L W E I
Honey Bee Apis mellifera XP_393399 493 55500 W418 W S F G I L L W E I Y S F G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795344 763 85563 Y689 S M S D V W S Y G I F M W E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 47.1 56.8 N.A. 87.1 82.2 N.A. N.A. 46.9 34 56 N.A. 24.8 40 N.A. 32.2
Protein Similarity: 100 64.6 64.6 58.8 N.A. 92.3 87.5 N.A. N.A. 65.6 49.2 71.4 N.A. 33.1 57.5 N.A. 42.9
P-Site Identity: 100 6.6 0 100 N.A. 100 6.6 N.A. N.A. 0 53.3 0 N.A. 13.3 0 N.A. 26.6
P-Site Similarity: 100 13.3 6.6 100 N.A. 100 13.3 N.A. N.A. 6.6 66.6 6.6 N.A. 46.6 33.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 42 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 17 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 34 0 0 17 0 9 34 0 9 17 17 0 % E
% Phe: 0 0 9 17 0 25 0 9 0 0 9 0 9 25 0 % F
% Gly: 0 0 9 9 17 0 9 0 50 0 0 0 0 9 42 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 17 0 0 0 25 17 0 9 0 9 % I
% Lys: 9 17 0 0 0 17 0 9 0 0 0 0 0 17 25 % K
% Leu: 34 34 0 0 25 9 25 17 9 9 9 9 0 0 9 % L
% Met: 0 9 9 0 9 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 34 0 34 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 9 % R
% Ser: 17 9 34 17 9 0 42 0 17 0 0 9 17 0 9 % S
% Thr: 0 0 9 0 0 9 9 0 0 0 0 0 0 0 0 % T
% Val: 17 0 9 0 34 0 0 25 0 0 9 17 0 0 0 % V
% Trp: 9 17 25 9 0 17 0 9 17 0 9 0 17 0 0 % W
% Tyr: 0 0 0 0 0 9 0 34 0 0 9 17 34 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _